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flhO [2019-02-27 18:46:28]
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flhO [2019-02-27 18:46:28]

flagellar basal-body rod protein, required for hook assembly
locus
BSU36400
pI
4.73
mw
29.28 kDa
protein length
270 aa Sequence Blast
gene length
813 bp Sequence Blast
function
motility and chemotaxis
product
flagellar basal-body rod protein
essential
no
synonyms
flgG,yvyA
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.1|Exponential and early post-exponential lifestyles] → [category|SW 4.1.1|Motility and chemotaxis] → [category|SW 4.1.1.2|Flagellar proteins]
  • [category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins]

    • Gene

    Coordinates
    3,746,279 3,747,091

    Phenotypes of a mutant

  • lack of [protein|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD]-dependent gene expression (no ''[gene|E0BB77C8F1220E931D16A1FA6B75AE8907C76FDB|hag]'' expression), no motility [Pubmed|22730131]
  • defective in swarming and flagellar assembly [pubmed|30201778]

    • The protein

    Catalyzed reaction/ biological activity

  • assembly of the flagellar hook [Pubmed|22730131]

    • Protein family

  • flagella basal body rod proteins family (according to Swiss-Prot)

    • Paralogous protein(s)

  • [protein|DC906ED8D787602B5796BAD8FD81F02C4BAC8D13|FlgE], [protein|13F35BC7EE8215D7A92A639BEB18647AC276D215|FlhP]

    • [SW|Localization]

  • extracellular (no signal peptide) [Pubmed|18957862]

    • Expression and Regulation

    Operons

    genes
    [gene|8EFE091CFB89FC406CD60776977C9C302C7826E0|flhO]-[gene|13F35BC7EE8215D7A92A639BEB18647AC276D215|flhP]
    description
    [Pubmed|15033535,22730131]

    sigma factors

  • [protein|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD]: sigma factor, [Pubmed|15033535,22730131], in [regulon|7024E4162A6D827069F882FDEACA696EBC05DD40|SigD regulon]
    • view in new tab

    Biological materials

    Mutant

  • BKE36400 ([gene|8EFE091CFB89FC406CD60776977C9C302C7826E0|flhO]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE36400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAATTTCCCACCTCTAAAA, downstream forward: _UP4_TAAGAAAACGGAAGAAAAAA
  • BKK36400 ([gene|8EFE091CFB89FC406CD60776977C9C302C7826E0|flhO]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK36400 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAAATTTCCCACCTCTAAAA, downstream forward: _UP4_TAAGAAAACGGAAGAAAAAA

    • References

    Reviews

  • 26490009

    • Original publications

  • 18957862,9023218,7836311,15033535,30201778